Effect of propolis on wound healing in sacrococcygeal pilonidal disease: A randomized controlled clinical trial Propolis is effective against Sacrococcygeal Pilonidal Sinus Research at Alanya Alaaddin Keykubat University invetsigated the wound healing effects of propolis in reported to have sacrococcygeal pilonidal sinus disease with a randomized controlled clinical trial. disease. A 15% propolis having anti-inflammatory, anti-oxidant, anti-bacterial, anti-fungal and immunostimulant properties was applied to the wound regions of a total of 33 patients who underwent marsupialization surgery. The patients were divided into study and control groups. The wound areas were analyzed post-operatively, on the 0, 7th, 14th, 28th days and on the day of complete recovery. An acceleration of wound healing with the administration of propolis was observed from the first week that was found to be even faster between days 14 and 28. The complete recovery score in the study group was significantly lower. The authors reported that propolis could be used to accelerate wound healing when the marsupialization method is preferred in patients diagnosed with uncomplicated sacrococcygeal pilonidal cyst due to its low cost, good patient compliance, low side effect profile, lack of toxicity and high efficacy.* *Kubat, M, Karabulut, Z, and Şengül, S. “Effect of propolis on wound healing in sacrococcygeal pilonidal disease: A randomized controlled clinical trial” Pak. J. Pharm. Sci., Vol.34, No.3(Suppl), May 2021, pp.1063-1067.

Source:  https://www.researchgate.net/publication/352833116_Effect_of_propolis_on_wound_healing_in_sacrococcygeal_pilonidal_disease_A_randomized_controlled_clinical_trial

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