Anti Wrinkle & Anti-Aging Natural Face Cream, Deep Wrinkle Treatment, Rejuvenating and Nourishing with Royal Jelly+Bee Venom Shea Butter, 1.7 fl. Oz
- Powerful 100% Natural Formula
- Reduces Fine Lines and Wrinkles
- Rejuvenates Skin
- Anti-Aging Moisturize
- Suitable for Every Skin Type
- Natural Immune Support
- High in Antioxidants
- 100% Natural
- Convenient to carry
- Sustainable and Eco-friendly
BEE&YOU APIBEAUTY ANTI-WRINKLE ANTI-AGING FACE CREAM
BEE&YOU Anti-Wrinkle & Anti-aging Face Cream is mainly formulated with royal jelly, bee venom, shea butter, Vit B5, Vit E, mineral zinc oxide, propolis extract, glycerin and aqua. Contains no chemicals..
Main Purpose of Use and Benefits:
POWERFUL 100% NATURAL FORMULA: Deeply penetrates within skin's surface and helps replenish dry skin, for radiant, younger-looking skin with Aqua, Glycerin, Zinc Oxide, Coconut Oil with Glycerin, Aloe Vera, Vegetable Glycerin with a mixture of citric-lactic-linoleic and oleic acid, Shea Butter, Olive Oil, Beeswax, Vit B5, Sodium Stearoyl Glutamate, Vit E Acetate, Magnesium Sulfate, Honey, Jasmine Oil (Parfum), Royal Jelly, Bee Venom.
REDUCES FINE LINES AND WRINKLES: helps reduce the look of deep wrinkles, including crow's feet, forehead, and cheek wrinkles and contains bee venom and royal jelly which adds plumping moisture to help hydrate and rejuvenate the look of skin.
REJUVENATES SKIN:: hydrates and plumps with moisture to rejuvenate the look of dull skin while working deep within skin's surface to reduce the look of wrinkles and diminish the look of dark spots.
ANTI-AGING MOISTURIZER: addresses multiple signs of aging skin in just 1 week: reduces wrinkles, re-firms contours, brightens skin, smooths skin roughness and deeply hydrates for younger-looking skin
SUITABLE FOR EVERY SKIN TYPE: dry skin, oily skin, combination skin, sensitive skin, and mature skin
Directions: Use every morning and night on dry and clean skin by massaging your face in circular motions. Use with Anti-aging Face Serum and Anti-aging Eye Serum for effective care of the whole face.
The above-listed effects were observed by healthy volunteers aged 33-70 who used this product for three weeks in a dermatological panel test. No irritation or allergenic reaction was observed by 15 volunteers, over 30 years old with sensitive skin, who used the products for three weeks in a dermatological patch test.
Yeditepe University (YÜ – AGAM, Istanbul, Turkey) carried out both tests.
What is Bee Venom?
Bee Venom is a complex mixture of proteins and amino acids, enzymes, sugars, and lipids. Melittin, a polypeptide is a major component of venom, and in humans it has the effect of stimulating the adrenal cortex (part of the adrenal gland) to release cortisol, a hormone associated with reducing inflammations and healing responses. Bee venom has been widely used as a cosmetic ingredient (topical agent) for promoting skin regeneration or a treatment of certain epidermal conditions. Topical application of bee venom can be well tolerated in the human skin because it has exhibited no dermal irritation potential in scientific studies. Long-term treatment with bee venom-containing cosmetics is safe because the irritation potential of bee venom is negligible.
Physical Properties of Bee Venom
Color Transparent liquid, dried venom color is light yellow or brown. This is because oxidation of some of the proteins of venom.
Odor Odorless, or honey like
Smell Ornamental pungent
Vitiligo: It is an abnormal pigmentation which is characterized by depigmentation of skin and hair. This is because of melanocyte proliferation, melanogenesis, and migration or increases in dendricity. As reported by Jeon et al. bee venom treatment elevates the melanocyte proliferation about two times as compared to the control in 1 week. By application of bee venom, the expression of MITF-M protein increases to the maximum level on third day and slowly decreases till fifth day. Bee venom treatment increases the ratio of cells with more than two dendrites by 23% in a time-dependent manner. The results showed that by bee venom treatment, the number of migrated cells as compared to the controls increases. It also induced melanocyte dendricity and melanocyte migration. The in-vitro study of bee venom has a positive effect on melanocyte proliferation, melanogenesis, dendricity, and migration. Thus, for treatment of vitiligo by repigmenting the skin, bee venom can be useful.
Facial Wrinkles: The beneficial effects of serum containing bee venom on facial wrinkles was studied by several scientific research where the application of bee venom serum resulted in decreased average wrinkle depth, total wrinkle area and count. It was also reported that the topical application of bee venom is safe for human use. Studies that were conducted on animals showed that it was well tolerated by them, and no dermal irritation was seen. Thus, application of bee venom is effective in improving the skin wrinkles thereby increasing the production of collagen and elastin.
Acne: As reported by Han et al. they performed a randomized double blind control trail where the therapeutic effects of bee venom on acne was examined. Subjective evaluation was done where bee venom on acne was applied by skin care products which contain bee venom and also products which do not contain bee venom for a period of 2 weeks. The results showed that the subjects that were applied cosmetics containing bee venom relatively showed a reduction by 57.5% in ATP levels, by the count of inflammatory & non-inflammatory lesions compared to the control, thereby measuring a decrease in the count of microbes. Therefore, Han et al. suggested that cosmetic containing bee venom is a good component as a therapeutic agent for acne.
Atopic Dermatitis: It is a type of skin disorder usually characterized by a defective skin barrier, drying of the skin, pruritus, eczema and also by some allergic responses. It is a chronic, inflammatory skin disorder which may worsen if not treated properly. Bee Venom because of its anti-inflammatory mechanism, it can be useful for treating atopic dermatitis. As reported by You et al. they did evaluation of about 136 subjects which were random distribution in different groups. Some subjects were applied bee venom containing moisturizer and silk protein and moisturizer without bee venom for a period of 4 weeks. The results indicates that application of the moisturizer with bee venom showed significantly lower eczema area and severity index and visual analogue scale, value compared to the patients who applied moisturizer without bee venom. There were as such no outstanding differences in the incidence of side effects induced by bee venom on the subject’s skin.
Applications of Bee Venom in Skin Care
Shrinks Pores: Bee venom is the best solution for pores. Its astringent properties help in removing excess oil and fluid from both the pores of skin and its uppermost layers.
Relieves Inflammation: One of the most important benefits of Bee Venom is its powerful anti-inflammatory effects. The soothing Adolapin which bee venom houses, it can quickly reduce the burning, redness, and swelling on skin.
Minimizes Wrinkles: Bee venom is known for its wrinkle-eliminating properties. It helps in stimulating blood flow inside body which makes the blood easier to flow to the surface of the skin. This ease of blood flow stimulates both the collagen and elastin production. Aside from this, what’s unique about Bee Venom is its ability to strengthen tissues to be able to stop premature aging.
Fades Blemishes: Bee venom properties which smooth are wrinkles & frown lines and shrink pores are also the ones who help fade acne blemishes. It also contains a peptide known as Melittin. Melittin has anti-bacterial and antimicrobial effects which are useful in fighting against acne.
Relaxes Muscles: The Bee Venom is helpful in relaxing the muscles as it strengths collagen and elastin to remain taut.
|Major Compounds of Bee Venom|
|Major Compounds of Bee Venom||Description|
|Melittin||It is the main component of Bee Venom which is a 26- residue peptide, accounting 40-60% of Venom’s composition. The peptide has carboxyl- terminal region which is hydrophilic in nature & is responsible for lytic action. The amino- terminal region is hydrophobic in nature with no lytic activity.|
|Apamin||It is an 18- amino acid peptide which contains two disulfide bridges. Apamin is the smallest neurotoxin in the Bee Venom. It constitutes about 2-3% dry weight of Bee Venom.|
|Adolapin||It is a polypeptide with 103 amino acids residue. It constitutes about 1% dry weight of Bee Venom.|
|Mast-Cell Degranulating (MCD) Peptide||The MCD peptide is also known as Peptide 401, which is a Bee Venom Polypeptide containing 22 amino acids which is similar to apamin structure where both of them contains two disulfide bonds. It constitutes about 2-3% dry weight of Bee Venom. The mast cell degranulating peptide echoes the biological action in histamine release from mast cells.|
|Phospholipase A2 (PLA2)||PLA2 is single polypeptide chain of about 128 amino acids containing about four sulfide bridges. It is the most fatal enzyme in the Bee Venom. Bee Venom PLA2 is about 12-15% of Bee Venom’s dry weight & very alkaline in nature.|
|Hyaluronidase||Hyaluronidase is responsible to break down hyaluronic acid in tissues. It allows the active component of Bee Venom to effectively diffuse into the victim’s tissue, responsible to affect the structural integrity and thereby increase the blood flow in that area. These actions combine together & increase the spreading of venom. It constitutes about 1.5-2% of dry weight of Bee Venom.|
|BEE&YOU Anti-aging Face Cream, 1.7 fl oz|
|Glycerin.||Natural compound derived from vegetable oils.||Moisturizer.|
|Zinc Oxide.||Mineral.||Helps protect cells from being damaged, halts the ageing process, and prevents skin dryness by filtering out the harmful UV rays.|
|Coco Caprylate / Caprate.||Coco Caprylate / Caprate a vegetable ingredient obtained from coconut.||Emollient, softness, penetrates deep and help skin to repair itself.|
|Aloe Barbadensis Leaf Juice.||Aloe Vera.||Burn healing, scar reducing, wounds healing, UV protection, rejuvenates aged tissues.|
|Glyceryl Citrate /Lactate /Linoleate / Oleate.||Esterified vegetable glycerin with a mixture of citric, lactic, linoleic, and oleic acid.||Act as lubricant, provides a soft, smooth appearance.|
|Butyrospermum Parkii (Shea) Butter.||A fat extracted from African shea tree.||Moisturizer, anti-inflammatory, and anti-aging properties.|
|Olea Europaea Oil.||Olive Oil.||Anti-inflammatory, anti-aging, and antioxidant, Nourishing, moisturizing, gives a silky-smooth softness.|
|Cera Alba.||Beeswax.||Promotes a healthy skin barrier and helps the skin retain moisture.|
|Panthenol.||Vitamin B-5.||Improve skin's hydration, elasticity, and smooth appearance. It also soothes red skin.|
|Sodium Stearoyl Glutamate.||Amino acid-based skin conditioning agent.||Helps maintain good skin condition..Emulsifier.|
|Tocopheryl Acetate.||Vitamin E acetate.||Prevent damage to skin caused by free radicals from UV exposure.|
|Magnesisum Sulfate.||White crystalline compound.||Dilutes other solids|
|Propolis Extract.||Extract of resin bee propolis.||Antioxidant and antimicrobial, good for acne-prone skin, reduces appereance of wrinkles and smooth out skin, recudes redness related to acne, allergies etc..|
|Honey.||Natural honeybee product.||Antimicrobial, good for acne-prone ski, moisturizes the skin.|
|Parfum.||Jasmine oil.||Antiseptic and anti-inflammatory, removes dark spots and unevenness, plus helps lighten acne scars over time, revealing healthy, radiant skin.|
|Royal Jelly.||Milky secretion produced by worker honeybees to feed queenbee.||Speeds up skin cell renewal and boosts collagen production.|
|Bee Venom.||Natural complex mixture of proteins and amino acids, enzymes, and lipids.||Powerful anti-inflammatory and increases blood circulation, gently plumping out and firming the skin, filling and smoothing fine lines and wrinkles.|